Select the incorrect match

Options

A. Transgenic mice-Polio vaccine
B. Rosie cow-`alpha` lactalbumin gene
C. ssDNA/RNA probe- Gene therapy
D. PCR - Molecular diagnosis

Answer

**Step-by-Step Solution:**

1. **Understand the Question**: The question asks to identify the incorrect match among the given options related to biotechnology.

2. **Analyze Each Option**:
- **Option A**: Transgenic mice are used for the preparation of the polio vaccine.
- **Evaluation**: This statement is correct. Transgenic mice can be engineered to produce proteins that are used in the development of vaccines, including the polio vaccine.

- **Option B**: Rosy cow has the alpha-lactalbumin gene.
- **Evaluation**: This statement is also correct. The rosy cow is a genetically modified organism that has been engineered to produce milk with a higher nutritional value by incorporating the alpha-lactalbumin gene.

- **Option C**: Single-stranded DNA or RNA probes are used in gene therapy.
- **Evaluation**: This statement is incorrect. In gene therapy, it is typically double-stranded DNA that is used, along with RNA probes, but single-stranded DNA is not commonly utilized in this context.

- **Option D**: PCR is used for molecular diagnosis.
- **Evaluation**: This statement is correct. PCR (Polymerase Chain Reaction) is a widely used technique in molecular biology for amplifying DNA, which is essential for various diagnostic purposes.

3. **Identify the Incorrect Match**: Based on the evaluations, Option C is the incorrect match as it incorrectly states that single-stranded DNA probes are used in gene therapy.

4. **Conclusion**: The incorrect match is Option C: Single-stranded DNA or RNA probe used in gene therapy.

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