RNAi result in

Options

A. Silencing of m-RNA translation
B. Silencing of a specific m-RNA due to complementary ds RNA molecule
C. Silencing of m-RNA molecule
D. Silencing of DNA for m-RNA transcription

Answer

**Step-by-Step Solution:**

1. **Understanding RNAi**: RNA interference (RNAi) is a biological process where RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules. This is a crucial mechanism for regulating gene expression and protecting against viral infections.

2. **Mechanism of RNAi**: When double-stranded RNA (dsRNA) is introduced into a cell, it triggers the RNAi pathway. The dsRNA is processed into small interfering RNA (siRNA) by an enzyme called Dicer. These siRNA molecules are then incorporated into a multi-protein complex known as the RNA-induced silencing complex (RISC).

3. **Targeting mRNA**: The siRNA within the RISC complex binds to complementary sequences on the target mRNA. This binding leads to the degradation of the mRNA, effectively silencing the gene associated with that mRNA.

4. **Consequences of RNAi**: As a result of this silencing, the translation of the mRNA into protein is inhibited. Without the production of specific proteins, the cellular functions that depend on those proteins are disrupted.

5. **Evaluating the Options**:
- Option 1: "Silencing of mRNA translation" - This is partially true but not the most accurate description of RNAi.
- Option 2: "Silencing of a specific mRNA due to complementary double-stranded RNA molecule" - This accurately describes the mechanism of RNAi.
- Option 3: "Silencing of mRNA molecule" - This is vague and does not capture the specificity of RNAi.
- Option 4: "Silencing of DNA from mRNA transcription" - This is incorrect as RNAi does not silence DNA.

6. **Conclusion**: The most accurate result of RNA interference is the silencing of a specific mRNA due to the complementary double-stranded RNA molecule.

**Final Answer**: RNAi results in the silencing of a specific mRNA due to complementary double-stranded RNA molecule.

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