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Assertion: In gene therapy of SCID, a pa...

Assertion: In gene therapy of SCID, a patient requires periodic infusion of genetically engineered lymphocytes
Reason :If the ADA gene is introducted into cells at early embryonic stage, it could be a permanent cure

A

If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion

B

It both Assertion & Reason are True but Reason is not a correct explanation of the Assetion

C

If Assertion is True but the Reason is False

D

If both Assertion & Reason are false

Text Solution

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The correct Answer is:
B
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Explore conceptually related problems

Why is repated transfusions of genetically engineered cells required in SCID patients?

Why is the introduction of genetically engineered lymphocytes into a ADA deficiency patient not a permanent cure ? Suggest a possible permanent cure.

Why is repeated transfusions of genetically engineered cells required in SCID patients?

(i) What is gene therapy? Name the first clinical case where it was used. (ii) Why is the introduction of genetically engineered lymphocytes into ADA deficiency patient not a permanent cure? Suggest a possible permanent cure.

Assertion: ADA deficiency can not be cured permanently by gene therapy Reason :The genetically engineered lymphocytes are immortal only in culture conditions

Introduction of ADA gene into bone marrow cells at embryonic stages may act as a permanent cure is which of the following disease ?

What is meant by ADA deficiency? How is gene therapy a solution to this problem? Why is it not a permanent cure?

Assertion: Genome of an organism can be changed for our benefit by genetic engineering Reason :Specific gene can be introduce into an organism for the synthesis of a desired product

Assertion : Meiosis produces four genetically dissimilar cells. Reason : Crossing over or gene exchange takes place in meiosis.

Study the following step which are followed during the process of gene therapy while treating a patient of SCID (i) Retrovirus infects lymphocytes extracted from bone marrow of the patient and cultured (ii) Engineered cells are injected into patient's bone marrow (iii) Normal allele is inserted into a retrovirus (iv) Retrovirus makes a DNA copy of its RNA. This DNA carrying the normal allele gets inserted into the chromosome of the host cell Arrangement the above given steps in correct sequence and select the correct option

ALLEN-BIOTECHNOLOGY AND MICROBES IN HUMAN WELFARE-Exercise IV
  1. Assertion: Gene therapy is a collection of methods that allows correct...

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  2. Assertion: ADA deficiency can not be cured permanently by gene therapy...

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  3. Assertion: In gene therapy of SCID, a patient requires periodic infusi...

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  4. Assertion: For effective treatement of a disease, early dignosis & und...

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  5. Assertion: ELISA is based on the principle of antigen antibody interac...

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  6. Assertion: PCR is a powerful technique to identify many genetic disord...

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  7. Assertion: A ds DNA, tagged with a radioactive molecule (probe) is use...

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  8. Assertion: Transgenic animals are those animals whose DNA is mainpulat...

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  9. How are the transgenic animals advantageous to us?

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  10. Assertion: The milk of 1^(st) transgenic cow, 'Rosie' is far better th...

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  11. Which of the following transgenic animals are being used to test the s...

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  12. Assertion: Transgenic animals are now used in toxicity testing of vari...

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  13. The use of bio-resources by multinational companies & other organisati...

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  14. Assertion: Bacillus thuringiensis is not killed by its own toxin Rea...

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  15. Assertion: The protein encoded by cry I Ab is not effective in control...

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  16. Assertion: GEAC will make decision regarding the validity of GM resear...

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  17. Assertion: Transgenic mice are beging developed for use in testing the...

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  18. Assertion: Bt -toxines kills the Bacillus thuringiensis Reason :Bt-t...

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  19. Assertion: Transgenic crops are avoided growing in areas where their ...

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  20. Read the given statements and select the correct option Statement 1 ...

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