Ketonuria & glycosuria is an indicative of-----------

Answer

**Step-by-Step Solution:**

1. **Understanding Ketonuria and Glycosuria:**
- Ketonuria refers to the presence of ketone bodies in the urine.
- Glycosuria refers to the presence of glucose in the urine.
- Both conditions indicate abnormal metabolic processes.

2. **Linking to Diabetes Mellitus:**
- Ketonuria and glycosuria are commonly associated with diabetes mellitus, a metabolic disorder.
- In diabetes mellitus, the body either does not produce enough insulin (Type 1) or cannot effectively use insulin (Type 2).

3. **Role of Insulin:**
- Insulin is a hormone produced by the beta cells of the pancreas.
- It helps regulate blood glucose levels by facilitating the uptake of glucose into cells and storing excess glucose as glycogen in the liver.

4. **Effects of Insulin Deficiency:**
- In the absence of sufficient insulin, glucose remains in the bloodstream, leading to hyperglycemia (high blood sugar).
- The kidneys filter excess glucose from the blood, which then appears in the urine (glycosuria).

5. **Protein Breakdown and Ketonuria:**
- When the body cannot utilize glucose for energy due to insulin deficiency, it starts breaking down fats and proteins for energy.
- This process produces ketone bodies, which can accumulate in the blood and be excreted in the urine (ketonuria).

6. **Conclusion:**
- Therefore, the presence of both ketonuria and glycosuria is indicative of diabetes mellitus, a condition characterized by impaired glucose metabolism and insulin deficiency.

**Final Answer:**
Ketonuria and glycosuria are indicative of diabetes mellitus.

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