Which cells of mucous layer of stomach secrete pepsinogen

Options

A. Chief cell
B. Goblet cell
C. Parietal cel
D. Oxyntic cell

Answer

**Step-by-Step Solution:**

1. **Identify the Cells in the Mucous Layer of the Stomach:**
- The stomach has various types of cells in its mucous layer, including chief cells, goblet cells, and parietal cells.

2. **Understand the Function of Chief Cells:**
- Chief cells, also known as peptic cells, are responsible for secreting pepsinogen, which is an inactive form of the enzyme pepsin.

3. **Define Pepsinogen:**
- Pepsinogen is a zymogen, meaning it is an inactive precursor of an enzyme. When it is activated, it becomes pepsin, which is essential for protein digestion.

4. **Differentiate Other Cell Types:**
- Goblet cells are primarily responsible for secreting mucus, which protects the stomach lining.
- Parietal cells (also known as oxyntic cells) secrete hydrochloric acid (HCl) and intrinsic factor, but they do not secrete pepsinogen.

5. **Conclusion:**
- The cells of the mucous layer of the stomach that secrete pepsinogen are the chief cells.

**Final Answer: Chief cells secrete pepsinogen in the mucous layer of the stomach.**

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