Pepsinogen is secreted by

Options

A. argentaffin cells
B. Goblet cells of ileum stimulates secretion of succus entricus
C. chief cells
D. parietal cells

Answer

**Step-by-Step Solution:**

1. **Understanding Pepsinogen**: Pepsinogen is an inactive precursor of the enzyme pepsin, which is crucial for protein digestion in the stomach.

2. **Location of Secretion**: Pepsinogen is secreted by specific cells located in the gastric glands of the stomach.

3. **Identifying the Cells**: The gastric glands contain different types of cells:
- **Mucous Cells**: Secrete mucus to protect the stomach lining.
- **Parietal Cells**: Secrete hydrochloric acid (HCl) and intrinsic factor.
- **Chief Cells**: These are the cells responsible for secreting pepsinogen.

4. **Activation of Pepsinogen**: Once pepsinogen is secreted, it is converted into its active form, pepsin, by the action of hydrochloric acid (HCl) secreted by parietal cells.

5. **Conclusion**: The correct answer to the question "Pepsinogen is secreted by" is the chief cells.

**Final Answer**: Pepsinogen is secreted by chief cells.

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