Secretin `:`

Options

A. Stimulates enzymes secretion by pancrea, inhibits acid secretion in stomach, stimulates gall bladder
B. Stimulates bicarbonate secretion by pancreas, inhibits acid secretion in stomach, stimulates bicarbonate secretion by liver
C. Stimulates acid secretion in stomach , potentiates action of CCK, inhibits intestinal movement
D. Stimulates gall bladder, inhibits acid secretion in stomach, stimulates bicarbonate secretion by pancres

Answer

**Step-by-Step Solution:**

1. **Understanding Secretin**: Secretin is a peptide hormone produced in the duodenum, which is the first part of the small intestine. It plays a crucial role in regulating digestive processes.

2. **Functions of Secretin**:
- **Inhibits Acid Secretion in the Stomach**: One of the primary functions of secretin is to inhibit the secretion of gastric acid from the stomach. This helps maintain a proper pH level in the duodenum, preventing damage to the intestinal lining.
- **Stimulates Bicarbonate Secretion by the Pancreas**: Secretin stimulates the pancreas to produce and secrete bicarbonate, which neutralizes stomach acid entering the duodenum.
- **Stimulates Bile Production in the Liver**: Secretin also stimulates the liver to produce bile, which is essential for the digestion and absorption of fats.
- **Coordinates with Cholecystokinin (CCK)**: Secretin works in conjunction with another hormone, CCK, to promote the release of bile from the gallbladder.

3. **Evaluating the Options**:
- **Stimulates enzyme secretion by pancreas**: Incorrect. Secretin does not stimulate enzyme secretion; it stimulates bicarbonate secretion.
- **Inhibits acid secretion in stomach**: Correct. Secretin inhibits gastric acid secretion.
- **Stimulates bicarbonate secretion by pancreas**: Correct. This is a primary function of secretin.
- **Stimulates bicarbonate secretion by liver**: Incorrect. Secretin does not stimulate bicarbonate secretion by the liver; it stimulates bile production.
- **Stimulates acid secretion in stomach**: Incorrect. Secretin inhibits acid secretion.
- **Stimulates gallbladder**: Correct. Secretin stimulates the gallbladder in coordination with CCK.

4. **Conclusion**: The correct functions of secretin include inhibiting acid secretion in the stomach, stimulating bicarbonate secretion by the pancreas, and stimulating the gallbladder. Therefore, the correct options are:
- Inhibits acid secretion in stomach
- Stimulates bicarbonate secretion by pancreas
- Stimulates gallbladder