Haldane effect is due to

Options

A. `CO_(2)`
B. Lactic acid
C. pH
D. Oxyheamoglobin

Answer

**Step-by-Step Solution:**

1. **Understanding the Haldane Effect**: The Haldane effect is a physiological phenomenon that describes how the presence of oxygen in the blood affects the ability of hemoglobin to bind with carbon dioxide (CO2).

2. **Role of Hemoglobin**: Hemoglobin is a protein in red blood cells that carries oxygen from the lungs to the rest of the body and helps transport carbon dioxide back to the lungs for exhalation.

3. **Carbon Dioxide and Oxyhemoglobin**: When hemoglobin binds with oxygen (forming oxyhemoglobin), it decreases its affinity for carbon dioxide. This means that as oxygen levels increase, the amount of carbon dioxide that hemoglobin can carry decreases.

4. **Location of the Effect**: The Haldane effect primarily occurs in the lungs, where oxygen concentration is high. Here, hemoglobin picks up oxygen and releases carbon dioxide.

5. **Conclusion**: The Haldane effect is primarily due to the presence of oxyhemoglobin, which affects how carbon dioxide is transported in the blood.

**Final Answer**: The Haldane effect is due to oxyhemoglobin (Option 4).

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