The chloride content of RBC will be higher than that of plasma in `:-`

Options

A. Systemic arteries and pulmonary veins
B. Systemic veins and pulmonary arteries
C. Systemic arteries and pulmonary arteries
D. Sstemic veins and pulmonary veins

Answer

To determine when the chloride content of red blood cells (RBCs) is higher than that of plasma, we need to consider the relationship between bicarbonate (HCO3-) and chloride ions (Cl-) in the blood. Here’s a step-by-step solution:

### Step-by-Step Solution:

1. **Understanding Chloride and Bicarbonate Relationship**:
- Chloride ions and bicarbonate ions have an inverse relationship in the blood. When the concentration of bicarbonate ions decreases, the concentration of chloride ions tends to increase in order to maintain electrical neutrality.

2. **Role of Hemoglobin**:
- Hemoglobin in RBCs binds to oxygen (O2) and carbon dioxide (CO2). When hemoglobin is saturated with oxygen, it tends to release CO2, which leads to a decrease in bicarbonate levels in the RBCs.

3. **Conditions for Higher Chloride Content**:
- The chloride content in RBCs will be higher than in plasma when the bicarbonate concentration is lower. This situation occurs when the blood is rich in oxygen and low in carbon dioxide.

4. **Identifying Relevant Blood Vessels**:
- This condition is typically found in systemic arteries and pulmonary veins. Systemic arteries carry oxygenated blood from the heart to the body, while pulmonary veins carry oxygenated blood from the lungs to the heart.

5. **Conclusion**:
- Therefore, the chloride content of RBCs will be higher than that of plasma in the systemic arteries and pulmonary veins, where the oxygen concentration is high and the carbon dioxide concentration is low.

### Final Answer:
The chloride content of RBC will be higher than that of plasma in **systemic arteries and pulmonary veins**.

---