Coronary heart disease is due to

Options

A. Streptococci bacteria
B. Inflammation of pericardium
C. Weakening of the heart valves
D. Insufficient blood supply to the heart muscles

Answer

**Step-by-Step Solution:**

1. **Understanding Coronary Heart Disease (CHD)**:
- Coronary heart disease occurs when the coronary arteries, which supply blood to the heart muscle, become narrowed or blocked.

2. **Role of Cholesterol**:
- High levels of cholesterol in the blood can lead to the accumulation of cholesterol particles on the walls of the arteries.

3. **Formation of Plaque**:
- This accumulation leads to the formation of plaque, which is a waxy substance that builds up in the arteries.

4. **Impact on Blood Flow**:
- The buildup of plaque narrows the coronary arteries, reducing the flow of oxygen-rich blood to the heart muscle.

5. **Consequences of Reduced Blood Supply**:
- Insufficient blood supply to the heart muscles can lead to chest pain (angina) or heart attacks, which are serious conditions associated with coronary heart disease.

6. **Evaluating Options**:
- The question provides several options regarding the cause of coronary heart disease:
- Option A: Streptococci bacteria - Incorrect.
- Option B: Inflammation of pericardium - Incorrect.
- Option C: Weakening of heart valves - Incorrect.
- Option D: Insufficient supply to the heart muscles - Correct.

7. **Conclusion**:
- Therefore, coronary heart disease is primarily due to insufficient blood supply to the heart muscles caused by plaque buildup in the coronary arteries.