Which one of the following couple were suggested by Doctors to not have more than one child

Options

A. `Rh^(+)` male and `Rh^(-)` female
B. `Rh^(-)` male and `Rh^(+)` female
C. `Rh^(+)` male and `Rh^(+)` female
D. `Rh^(-)` male and `Rh^(-)` female

Answer

To solve the question of which couple was suggested by doctors to not have more than one child, we need to analyze the options based on Rh incompatibility.

### Step-by-Step Solution:

1. **Understanding Rh Factor**:
- The Rh factor is a protein that can be present on the surface of red blood cells. Individuals with this protein are Rh positive (Rh+), while those without it are Rh negative (Rh-).

2. **Identifying the Couples**:
- The options provided are:
- A) Rh positive male and Rh negative female
- B) Rh negative male and Rh positive female
- C) Rh positive male and Rh positive female
- D) Rh negative male and Rh negative female

3. **Analyzing Rh Incompatibility**:
- Rh incompatibility occurs when an Rh negative mother is pregnant with an Rh positive child. This can lead to complications in subsequent pregnancies.

4. **Mechanism of Erythroblastosis Fetalis**:
- If an Rh negative female (mother) carries an Rh positive child (father), during delivery, the mother’s blood may mix with the baby’s blood. This can cause the mother to produce antibodies against the Rh positive antigen.
- In a subsequent pregnancy with another Rh positive child, these antibodies can attack the baby's red blood cells, leading to a condition known as erythroblastosis fetalis.

5. **Conclusion**:
- Therefore, the couple that should be advised not to have more than one child is the **Rh positive male and Rh negative female** (Option A), as the risk of complications increases with each subsequent pregnancy.

### Final Answer:
The couple suggested by doctors to not have more than one child is **Rh positive male and Rh negative female**.

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