Due to which reason, defect in kidney leads to anaemia ?

Options

A. No secretion of erythropoietin
B. Reduce vitamin `B_(12)`
C. decrease reagborbtion of water
D. Loss of haemoglobin in urine

Answer

**Step-by-Step Solution:**

1. **Understanding the Role of Kidneys**: The kidneys are vital organs that perform multiple functions, including the regulation of blood pressure, electrolyte balance, and the production of hormones.

2. **Erythropoietin (EPO) Production**: One of the key hormones produced by the kidneys is erythropoietin (EPO). EPO is a glycoprotein that stimulates the production of red blood cells (RBCs) in the bone marrow.

3. **Impact of Kidney Defect**: When there is a defect in the kidneys, the production of erythropoietin is significantly reduced or may cease altogether. This reduction means that there is less stimulation for the bone marrow to produce red blood cells.

4. **Consequences of Reduced RBC Production**: With fewer red blood cells being produced, the oxygen-carrying capacity of the blood decreases, leading to a condition known as anemia. Anemia is characterized by fatigue, weakness, and pallor due to insufficient hemoglobin in the blood.

5. **Conclusion**: Therefore, the primary reason a defect in the kidney leads to anemia is the "no secretion of erythropoietin." This lack of EPO results in decreased red blood cell production, which is the direct cause of anemia.

**Final Answer**: The defect in the kidney leads to anemia due to the no secretion of erythropoietin.

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