Opium is not much clinically used because :-

Options

A. Less potent drug
B. Shows physical dependency
C. Toxicity present in our body
D. Prolonged used as medicine

Answer

### Step-by-Step Solution:

1. **Understanding Opium**: Opium is a narcotic drug derived from the opium poppy. It contains several alkaloids, including morphine and codeine, which are known for their pain-relieving properties.

2. **Mechanism of Action**: Opium acts on the opioid receptors in the central nervous system (CNS) and gastrointestinal tract. These receptors are responsible for pain modulation, reward, and addictive behaviors.

3. **Potency of Opium**: While opium is a potent analgesic (pain reliever), its clinical use is limited due to certain risks associated with its consumption.

4. **Physical Dependency**: One of the major concerns with opium is the development of physical dependency. When a person uses opium regularly, their body can become accustomed to its presence, leading to withdrawal symptoms if the drug is suddenly stopped.

5. **Consequences of Dependency**: The physical dependency can evolve into psychological or physiological dependency, where the individual feels compelled to continue using the drug to avoid discomfort or to experience its effects.

6. **Clinical Implications**: Due to the high potential for dependency and addiction, healthcare providers are cautious about prescribing opium. This leads to its limited clinical use despite its effectiveness as a pain reliever.

7. **Conclusion**: Therefore, the primary reason opium is not much clinically used is due to the risk of physical dependency and the potential for addiction, which outweighs its benefits in many cases.