In simplified version of nucleic acid chain, nucleotides are joined together by

Options

A. `beta-` glycosidic linkage
B. phosphodiester linkage
C. `alpha-` glycosidic linkage
D. peptide linkage

Explanation

To solve the question regarding how nucleotides are joined together in a simplified version of a nucleic acid chain, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Nucleotides**:
- Nucleotides are the building blocks of nucleic acids (DNA and RNA). Each nucleotide consists of three components: a nitrogenous base, a pentose sugar (ribose in RNA and deoxyribose in DNA), and a phosphate group.

2. **Structure of Nucleic Acids**:
- In a nucleic acid chain, nucleotides are linked together to form a long chain. The structure of nucleic acids can be simplified to show how these nucleotides connect.

3. **Identifying the Linkage**:
- The connection between nucleotides occurs through specific chemical bonds. In nucleic acids, the phosphate group of one nucleotide connects to the sugar of the next nucleotide.

4. **Type of Bond Formed**:
- The bond that forms between the phosphate group of one nucleotide and the sugar of the next nucleotide is known as a phosphodiester bond. This bond is crucial for the backbone structure of nucleic acids.

5. **Conclusion**:
- Therefore, in a simplified version of a nucleic acid chain, nucleotides are joined together by a **phosphodiester linkage**.

### Final Answer:
Nucleotides in a nucleic acid chain are joined together by **phosphodiester linkage**.