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R-overset(O)overset(||)C-H+ NH3 + HCN to...

`R-overset(O)overset(||)C-H+ NH_3 + HCN to A overset(H_3 O^(+))to B` respectively A and B can be

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To solve the problem, we will break down the reaction step by step, identifying the compounds A and B formed during the process. ### Step 1: Identify the Reactants The reaction starts with an aldehyde (R-CHO), ammonia (NH₃), and hydrogen cyanide (HCN). ### Step 2: Protonation of the Aldehyde The aldehyde (R-CHO) is protonated by an acid (H₃O⁺) to form a more electrophilic species. This step enhances the reactivity of the carbonyl carbon. **Hint:** Protonation increases the electrophilicity of the carbonyl carbon. ### Step 3: Nucleophilic Attack by Ammonia Ammonia (NH₃) acts as a nucleophile and attacks the electrophilic carbon of the protonated aldehyde. This results in the formation of an intermediate that has both an amine (NH₂) and a hydroxyl (OH) group. **Hint:** Remember that nucleophiles attack electrophilic centers. ### Step 4: Formation of the Iminium Ion The intermediate undergoes dehydration (loss of water) to form an iminium ion (R-NH=CH₂). This step is crucial as it sets the stage for the next nucleophilic attack. **Hint:** Dehydration often leads to the formation of double bonds in organic reactions. ### Step 5: Nucleophilic Attack by Cyanide Ion The iminium ion is then attacked by the cyanide ion (CN⁻), leading to the formation of a new compound (R-NH-C≡N). **Hint:** The cyanide ion is a strong nucleophile and can attack the iminium ion. ### Step 6: Hydrolysis of the Cyanohydrin The product from the previous step undergoes hydrolysis in the presence of water (H₂O) and acid (H₃O⁺) to form a cyanohydrin (R-NH-CH(OH)-C≡N). **Hint:** Hydrolysis typically involves the addition of water to break bonds. ### Step 7: Protonation and Formation of the Amino Acid The cyanohydrin undergoes further reactions, including protonation and eventual hydrolysis, leading to the formation of an amino acid (R-NH₂-CH₂-COOH). **Hint:** The final product is an amino acid, which contains both an amine and a carboxylic acid functional group. ### Summary of Products - **Compound A:** The product after the nucleophilic attack of cyanide on the iminium ion, which can be represented as R-NH-C≡N. - **Compound B:** The final amino acid product formed after hydrolysis, represented as R-NH₂-CH₂-COOH. ### Final Answer - **A:** R-NH-C≡N (an intermediate compound) - **B:** R-NH₂-CH₂-COOH (an amino acid)
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