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The defect sickle-cell anaemia is caused...

The defect sickle-cell anaemia is caused by the `"_____"` of glutamic acid by the valine at the `6^(th)` position of the `"_____"` globin chain of the haemoglobin molecule.

A

rusting easily

B

stone cancer in Taj Mahal

C

non-fertility of soil

D

all are correct

Text Solution

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The correct Answer is:
D
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Assertion :-Sickle-cell anaemia is caused by the substitution of glutamic acid by valine at the sixth position of the beta globin chain of the hemoglobin moecule. Reason :- It is due to the single base substitution at the sixth codon of the beta globin gene from GUG to GAG.

Sickle-cell anaemia is caused due to the substitution of :

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Sickle-cell anaemia is caused by a substitution mutation. At this sixth position of haemoglobin, ………... due to this mutation

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