Explain Erythroblastosis foetalis

Explanation

Erythroblastosis foetalis is caused by the Rh factor incompatiblility in child birth . If a Rh negative women marries a Rh positive man the foetus may be Rh positive inherited from its father . The mother having Rh positive foetus in her womb becomes immune logically sensitized. The mother.s blood recognizes the Rh antigen due to damages of blood vesels during child birth . the child is delivered before these processes of anti D antibody production by the sensitized mother. Hence there is no affect associated with the exposure of the mother to Rh positive antigen during first child birth . but in subsquent pregnancy by the same mother the child is exposed to antibody produced by mother against Rh antigen which are carried across placenta into foetal circulation that causes haemolysis of foetal RBC . this reulsts in anaemia or haemolytic joundice, Which is called as Erythroblastosis foetalis or Haemolytic disease of new born (HDN) .