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From their examination of the structure ...

From their examination of the structure of DNA, What did Watson and Crick infer about the probable mechanism of DNA replication, coding capability and mutation?

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Watson and Crick in 1953 proposed semi-conservative mechanism of DNA replication based on DNA model. They were on the opinion that the two polynucleotide strands of DNA molecule unwind and start separating at one end. The covalent hydrogen bonds are broken during this process. The separated single strand DNA acts as a template for the synthesis of new strand. Therefore each double helix daughter DNA carries one polynucleotide strand from the parent DNA, which acts as a template and other polynucleotide strand is newly synthesized and complementary to the parent strand.

(ii) Watson and Crick inferred that the DNA strands have the capacity to pass on genetic information to the RNA
(iii) DNA replication `to` (Transcription) RNA `to` (Translation) Protein
(iv) They also inferred that nucleic acids are able to undergo sudden changes in structure, which is termed as mutation.
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