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Explain the formation of a nucleosome....

Explain the formation of a nucleosome.

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Nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a cre a histones.
In eukaryotes, the formation of nucleosome is much more complex. Chromatin is formed by a series of repeating units of nucleosomes. Kornberg proposed a model for the nuclesome. Histone octamere is an unit of two molecules of the four histone proteins, H2A, H2B, H3 and H4. The negatively charged DNA is wrapped around positively charged histone octamere to form a structure known as nucleosome.
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