Read the following text and answer the following questions on the basis of the same:
Mutation is sudden, discontinuous variation in genotype of an organism due to a change in its chromosomes and genes. Variation in DNA is a result of mutation. It is of three types : Gene mutation, chromosomal aberrations and gametic mutation. Gametic mutation is a change in chromosome number that brings effect on the phenotype, it is of two type - aneuploidy and euploidy. Mutation can be artificially produced by certain agents called mutagen. There are two major types of mutagens: physical and chemical mutagen.
Change in sequence of nucleotide in DNA is known as ...... .

Options

A. Translation
B. Recombination
C. Mutation
D. Transcription

Explanation

**Step-by-Step Text Solution:**

1. **Understanding Mutation**: The passage defines mutation as a sudden and discontinuous variation in the genotype of an organism, which occurs due to changes in its chromosomes and genes.

2. **Types of Mutation**: It mentions three types of mutations: gene mutation, chromosomal aberrations, and gametic mutation.

3. **Focus on Gene Mutation**: The question specifically asks about the change in the sequence of nucleotides in DNA. This is directly related to gene mutation, which involves alterations in the nucleotide sequence.

4. **Identifying the Correct Term**: The question provides four options: translation, recombination, mutation, and transcription. Among these, the term that best describes a change in the nucleotide sequence is "mutation".

5. **Conclusion**: Therefore, the answer to the question "Change in sequence of nucleotide in DNA is known as..." is **mutation**.

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