Write brief note on the following
Humulin

Explanation

Genentecl the first biotech company to manufacture recombinant human insulin in 1978 using. bacteriophage vector and E. coli as the cloning and expression host cell.. Later, this technology was licenced to Eli Lilly Corporation of USA.
The recombinant human insulin was termed as Humulin. It was approved as the first recombinant drug by the Food and Drug Administration (FDA), USA for human use. Since then, several companies all over the world have been manufacturing recombinant human insulin on a commercial basis.
Some noteworthy companies are Novo Nordisk of Denmark, Hoechst and Aventis of Germany and Pfizer of USA. Wokhardt Limited, a pharmaceutical company has been manufacturing human insulin in India under the trade name of Wosulin.