Due to nondisjunction of chromosomes during spermatogensis, some sperms carry both sex chromosomes (22A + XY) and some sperms do not carry any sex chromosome (22A + O). If these sperms fertilise normal eggs (22A + X), what types of genetic disorders respectively appear among the offspring ?

Options

A. Klinefelter's syndrome and Turner's syndrome
B. Turner's syndrome and Klinefelter's syndrome
C. Down's syndrome and Turner's syndrome
D. Down's syndrome and cri-du-chat syndrome

Answer

A

Explanation

Turner's syndrome is due to monosomy `(2n-1)`. It occurs by the union of an allosome free egg `(22+0)` and a normal X sperm or a normal egg and an allosperm free sperm `(22+0)`
Turner's syndrome (most common type of female genetic disease) havinf XO genotype is caused by the absence of X chromosomes in female. These are sterile females with poorly developed ovariesm small uterus and underdeveloped breasts. They have webbed neck and broad chest. The individual gas 2n = 45 chromosomes `(44 + XO)` instead of 46
For klinefelter's syndrome.