Assertion : Phenylpyruvic acid is excreted through urine in case of phenylketonuria
Reason : The affected individual lacks enzyme phenylalanine hydroxylase.

Options

A. Both A and R are correct and R is correct explanation of A
B. Both A and R are correct but R is not the correct explanation of A
C. A is correct but R is incorrect
D. Both A and R are incorrect

Answer

A

Explanation

Phenylketonuria is an inherited error of metabolism caused by a deficiency in the enzyme phenylalanine hydroylase it is an autosomal recessive trait. It is a hereditary human condition resulting from the inability to convert phenylalanine into tyrosine. This leads to phenylpyruvic acid and other derivatives. These are then excreted in urine due to poor absorption by kidneys.