A reaction that converts an amide into an amine is called

Options

A. Hofmann bromamide reaction
B. Gattermann Koch reaction
C. Carbylamine reaction
D. Gabriel phthalimide reaction

Answer

To solve the question "A reaction that converts an amide into an amine is called," we need to analyze the given options and identify the correct reaction.

### Step-by-Step Solution:

1. **Understanding the Structures**:
- An **amide** has the general structure R-C(=O)-NH2, where R is a hydrocarbon group.
- An **amine** is a compound derived from ammonia (NH3) by replacing one or more hydrogen atoms with hydrocarbon groups.

2. **Identifying the Reactions**:
- **Hoffman Bromamide Reaction**: This reaction involves the conversion of an amide to a primary amine using bromine (Br2) in the presence of a strong base like sodium hydroxide (NaOH). The reaction results in the loss of one carbon atom from the amide.
- **Gatterman Koch Reaction**: This reaction is related to the synthesis of aldehydes from benzene and is not relevant to the conversion of amides to amines.
- **Carbill Amine Reaction**: This reaction involves the formation of isocyanides from primary amines and chloroform in the presence of a base, which does not convert amides to amines.
- **Gabriel Thalymide Reaction**: This reaction is used for the synthesis of primary amines from thalamide, but it does not directly convert amides to amines.

3. **Conclusion**:
- The only reaction from the options that converts an amide to an amine is the **Hoffman Bromamide Reaction**.

### Final Answer:
The reaction that converts an amide into an amine is called the **Hoffman Bromamide Reaction**.

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