Give the karyotype of Klinefelter's syndrome:
a) XO, 45
b) XX, 46
c) XXY, 47
d) XYY, 47

Options

A. XO, 45
B. XX, 46
C. XXY, 47
D. XYY, 47

Explanation

To determine the karyotype of Klinefelter's syndrome, we need to analyze the chromosomal composition associated with this condition. Klinefelter's syndrome is a genetic disorder that occurs in males due to the presence of an extra X chromosome.

### Step-by-Step Solution:

1. **Understanding Klinefelter's Syndrome**:
- Klinefelter's syndrome is characterized by the presence of one or more extra X chromosomes in males. The typical male karyotype is 46,XY, which means there are 46 chromosomes in total, with one X and one Y chromosome.

2. **Identifying the Karyotype**:
- In Klinefelter's syndrome, the most common karyotype is 47,XXY. This means that there are 47 chromosomes in total, with two X chromosomes and one Y chromosome.

3. **Analyzing the Options**:
- a) XO, 45: This represents Turner syndrome, not Klinefelter's.
- b) XX, 46: This represents a normal female karyotype.
- c) XXY, 47: This is the correct karyotype for Klinefelter's syndrome.
- d) XYY, 47: This represents another condition known as XYY syndrome.

4. **Conclusion**:
- Based on the analysis, the correct answer is **c) XXY, 47**.