The synthesis of RNA primer complimentary to the DNA template strand is assisted by:
a) Primase
b) DNA polymerase III
c) Helicase
d) Ligase

Options

A. Primase
B. DNA polymerase III
C. Helicase
D. Ligase

Explanation

To answer the question regarding which enzyme assists in the synthesis of an RNA primer complementary to the DNA template strand, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Role of RNA Primer**:
- In DNA replication, an RNA primer is necessary to initiate the synthesis of a new DNA strand. This primer provides a free 3' hydroxyl group for DNA polymerase to extend the new strand.

2. **Identifying the Enzymes**:
- The question provides four options: Primase, DNA polymerase III, Helicase, and Ligase. We need to analyze the function of each enzyme in the context of DNA replication.

3. **Analyzing Each Option**:
- **a) Primase**: This enzyme synthesizes the RNA primer by adding RNA nucleotides complementary to the DNA template strand. It is crucial for starting the replication process.
- **b) DNA polymerase III**: This enzyme is responsible for adding nucleotides to the growing DNA strand but requires a primer to start. It does not synthesize the primer itself.
- **c) Helicase**: This enzyme unwinds the double-stranded DNA, separating the two strands to allow replication to occur. It does not synthesize the primer.
- **d) Ligase**: This enzyme joins Okazaki fragments on the lagging strand after they have been synthesized. It does not play a role in primer synthesis.

4. **Conclusion**:
- Based on the functions of these enzymes, the one that specifically synthesizes the RNA primer is **Primase**. Therefore, the correct answer is **a) Primase**.

### Final Answer:
The synthesis of RNA primer complementary to the DNA template strand is assisted by: **a) Primase**.

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