Chromosomal disorders are caused due to absence or excess or abnormal arrangement of one or more chromosomes. Failure of segregation of chromatids during cell division cycle results in the gain or loss of a chromosome, and is called aneuploidy. Failure of cytokinesis after telophase stage of cell division results in an increase in a whole set of chromosomes in an organism and, this is known as polyploidy.
There are a total number of .......... pairs of autosomes in a normal human cell.

Options

A. 22
B. 23
C. 24
D. 25

Explanation

To solve the question regarding the number of pairs of autosomes in a normal human cell, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Chromosomes in Humans:**
- A normal human cell contains a total of 46 chromosomes. This is denoted as 2n = 46, where 'n' represents the number of pairs of chromosomes.

2. **Identifying Chromosome Types:**
- Among these 46 chromosomes, there are two types: autosomes and sex chromosomes.
- Autosomes are chromosomes that do not determine sex, while sex chromosomes are involved in determining the sex of an individual.

3. **Counting the Chromosome Pairs:**
- Since humans are diploid organisms, the chromosomes are arranged in pairs. Therefore, the 46 chromosomes can be grouped into 23 pairs (46 divided by 2).

4. **Distinguishing Autosomes from Sex Chromosomes:**
- Out of the 23 pairs, 22 pairs are classified as autosomes. These are responsible for the majority of genetic traits and functions.
- The remaining 1 pair consists of sex chromosomes (XX in females and XY in males).

5. **Conclusion:**
- Thus, the total number of pairs of autosomes in a normal human cell is 22.

### Final Answer:
There are a total of **22 pairs of autosomes** in a normal human cell.

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