Select the most appropriate option, out of the five options given for each of the following sentences, which in vour view, should be grammatically and structurally correct. Please note that the meaning and the context of the sentence must not change.

Options

A. The patient reported the doctor that the medicine had severely affected at him.
B. The patient reported the doctor that the medicine had severely affected to him.
C. The patient reported to the doctor that the medicine had severely affected on him.
D. The patient reported the doctor that the medicine had severely affected him.