Splitting of centromeres is observed in _________ stage of mitosis cell division.

Explanation

**Step-by-Step Text Solution:**

1. **Understanding Centromeres**: The centromere is a specialized region of a chromosome that plays a crucial role during cell division. It is the point where two sister chromatids are joined together.

2. **Phases of Mitosis**: Mitosis is divided into several stages: prophase, metaphase, anaphase, and telophase. Each stage has specific events that occur.

3. **Identifying the Stage**: The question asks about the specific stage in which the centromeres split. During mitosis, the splitting of centromeres is a key event that allows sister chromatids to separate and move to opposite poles of the cell.

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