Division of centromere and chromatids takes place between which stages of mitotic cell division?

Options

A. Prophase and metaphase.
B. Metaphase and anaphase.
C. Anaphase and telophase.
D. Telophase and prophase.

Answer

**Step-by-Step Solution:**

1. **Understanding the Stages of Mitosis**: Mitosis consists of several stages: prophase, metaphase, anaphase, and telophase. Each stage has specific events that occur.

2. **Identifying the Role of Centromeres and Chromatids**: The centromere is the region of a chromosome where sister chromatids are joined. During mitosis, the separation of sister chromatids is crucial for proper cell division.

3. **Analyzing the Options**:
- **Prophase and Metaphase**: In prophase, chromosomes condense, and the nuclear envelope breaks down, but the centromeres do not divide yet. During metaphase, chromosomes align at the equatorial plane, but the centromeres are still intact.
- **Metaphase and Anaphase**: This is the correct option. During metaphase, chromosomes are aligned, and in anaphase, the centromeres divide, allowing the sister chromatids to separate and move towards opposite poles.
- **Anaphase and Telophase**: In anaphase, the centromeres divide, but by telophase, the chromatids have already separated, and the cell is preparing to divide.

4. **Conclusion**: The division of centromere and chromatids occurs between the stages of metaphase and anaphase.

**Final Answer**: The division of centromere and chromatids takes place between the stages of **metaphase and anaphase**.

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