In globular proteins:

Options

A. polypeptide chains are arranged as coil
B. spherical in shape
C. water soluble
D. all of these

Explanation

### Step-by-Step Solution:

1. **Understanding Globular Proteins**:
- Globular proteins are a category of proteins that are generally soluble in water and have a spherical shape. This characteristic is crucial for their function in biological systems.

2. **Structure of Globular Proteins**:
- The polypeptide chains in globular proteins are arranged in a coiled or folded manner. This coiling allows for the formation of a compact structure, which is essential for their solubility and functionality.

3. **Examples of Globular Proteins**:
- Common examples of globular proteins include hemoglobin and myoglobin. Hemoglobin is responsible for oxygen transport in the blood, while myoglobin stores oxygen in muscle tissues.

4. **Key Characteristics**:
- To summarize, the key characteristics of globular proteins are:
- They are water-soluble.
- They have a spherical shape.
- Their polypeptide chains are arranged in a coiled structure.

5. **Conclusion**:
- Based on the above points, the correct statement regarding globular proteins is that their polypeptide chains are arranged as a coil, they are spherical in shape, and they are water-soluble.

### Final Answer:
The correct statement related to globular proteins is that their polypeptide chains are arranged as a coil, they are spherical in shape, and they are water-soluble.