Vaccine contains:

Options

A. live microbes
B. dead microbes
C. weakend microbes
D. Both (B) and (C)

Explanation

### Step-by-Step Solution:

1. **Understanding Vaccines**: Vaccines are biological preparations that provide immunity to a particular infectious disease. They typically contain components that stimulate the immune system.

2. **Components of Vaccines**: The main components found in vaccines are strains of viruses or bacteria. These can be either live, weakened (attenuated), or killed (inactivated) forms of the pathogens.

3. **Types of Microbes in Vaccines**:
- **Live Microbes**: These are active forms of the pathogen that can cause disease. Vaccines generally do not use live microbes that can cause illness.
- **Dead Microbes**: These are killed pathogens that cannot cause disease but can still provoke an immune response. They are commonly used in vaccines.
- **Weakened Microbes**: These are live microbes that have been altered so they do not cause disease but still elicit a strong immune response.

4. **Conclusion**: Based on the information, vaccines primarily contain dead or weakened microbes. Therefore, the correct answer to the question "Vaccine contains:" would be dead microbes and/or weakened microbes.