Distinction of prokaryotes and eukaryotes is based on:

Options

A. proteins
B. nucleus
C. plasma membrane
D. DNA

Explanation

To distinguish between prokaryotes and eukaryotes, we can follow these steps:

### Step-by-Step Solution:

1. **Definition of Prokaryotes and Eukaryotes**:
- Prokaryotes are unicellular organisms that lack a true nucleus and membrane-bound organelles. Examples include bacteria and archaea.
- Eukaryotes are organisms whose cells contain a nucleus and other organelles enclosed within membranes. This group includes animals, plants, fungi, and protists.

2. **Presence of Nucleus**:
- The primary distinction between prokaryotes and eukaryotes is the presence or absence of a nucleus.
- Eukaryotic cells have a well-defined nucleus that houses their genetic material (DNA).
- Prokaryotic cells do not have a nucleus; instead, their genetic material is located in a region called the nucleoid.

3. **Organelles**:
- Eukaryotic cells contain various membrane-bound organelles (like mitochondria, endoplasmic reticulum, Golgi apparatus, etc.), while prokaryotic cells do not have these structures.

4. **Size and Complexity**:
- Prokaryotic cells are generally smaller and simpler in structure compared to eukaryotic cells, which are larger and more complex.

5. **Reproduction**:
- Prokaryotes typically reproduce asexually through binary fission, while eukaryotes can reproduce both asexually and sexually.

6. **Conclusion**:
- The distinction between prokaryotes and eukaryotes is primarily based on the presence of a nucleus and the complexity of cellular structures.