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Consider the first reaction of TCA cycle...

Consider the first reaction of TCA cycle.
Acetyl `CoA+OA A+H_(2)O overset("Citrate synthase")to`
`" " (A)+CoA.`
What is true about compound A?

A

First product of TCA cycle

B

Tricarboxylic acid and six carbon compound

C

It undergoes recorganization in the presence of enzyme aconitase to form cis-aconitate

D

All of these

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AI Generated Solution

The correct Answer is:
To solve the question regarding compound A in the first reaction of the TCA cycle, we will follow these steps: ### Step-by-Step Solution: 1. **Identify the Reactants**: The first reaction of the TCA cycle involves acetyl CoA and oxaloacetate (OAA) reacting in the presence of the enzyme citrate synthase, along with water. 2. **Understand the Reaction**: The reaction can be summarized as: \[ \text{Acetyl CoA} + \text{OAA} + \text{H}_2\text{O} \overset{\text{Citrate synthase}}{\rightarrow} \text{Compound A} + \text{CoA} \] Here, acetyl CoA (a 2-carbon molecule) combines with oxaloacetate (a 4-carbon molecule) to form compound A. 3. **Determine the Product**: When acetyl CoA (2 carbons) and oxaloacetate (4 carbons) combine, they form citrate, which is a 6-carbon compound. Therefore, compound A is citrate. 4. **Characterize Compound A (Citrate)**: - **First Product of TCA Cycle**: Citrate is indeed the first product formed in the TCA cycle. - **Carboxylic Acid**: Citrate is a tricarboxylic acid, meaning it has three carboxyl (-COOH) groups. - **Carbon Count**: Citrate contains 6 carbon atoms. 5. **Conclusion**: Based on the above points, we can conclude that compound A is citrate, and it possesses the following characteristics: - It is the first product of the TCA cycle. - It is a tricarboxylic acid. - It is a 6-carbon compound. ### Final Answer: Compound A is citrate, which is the first product of the TCA cycle, a tricarboxylic acid, and contains 6 carbon atoms. ---
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