)Ilow metabolic rate
II)Increase in body weight
III)Tendency to retain water in tissue
Which of the following disease shows the above given symptoms?

Options

A. Gigantism
B. Cretenism
C. Myxoedema
D. Acromegaly

Answer

To solve the question regarding which disease exhibits the symptoms of low metabolic rate, increase in body weight, and tendency to retain water in tissues, we can follow these steps:

### Step 1: Identify the Symptoms
The symptoms provided are:
1. Low metabolic rate
2. Increase in body weight
3. Tendency to retain water in tissues

### Step 2: Analyze the Options
The options given are:
1. Gigantism
2. Creatinism
3. Myxedema
4. Acromegaly

### Step 3: Understand Each Condition
- **Gigantism**: Caused by hypersecretion of growth hormone, leading to excessive growth in children. It does not typically present with low metabolic rate or water retention.

- **Creatinism**: A condition resulting from severe hypothyroidism in infancy, leading to stunted physical and mental growth. While it is related to thyroid issues, it does not specifically present with all the symptoms listed.

- **Myxedema**: This is a severe form of hypothyroidism in adults. It is characterized by low metabolic rate, weight gain, and water retention in tissues due to the accumulation of glycosaminoglycans in the skin.

- **Acromegaly**: Similar to gigantism, but occurs in adults due to excess growth hormone. It leads to abnormal growth of bones and tissues but does not correlate with low metabolic rate or water retention.

### Step 4: Conclusion
Based on the analysis, the disease that shows the symptoms of low metabolic rate, increase in body weight, and tendency to retain water in tissues is **Myxedema**.

### Final Answer
The correct answer is **Myxedema** (Option C).

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