During this phase of cell cycle, cell is metabolically active without duplication of DNA

Options

A. M-phase
B. S-phase
C. `G_(1)` phase
D. `G_(2)` phase

Answer

To solve the question "During this phase of cell cycle, cell is metabolically active without duplication of DNA," we will analyze each of the provided options step by step.

### Step-by-Step Solution:

1. **Understanding the Cell Cycle Phases**:
- The cell cycle consists of several phases: G1 phase, S phase, G2 phase, and M phase. Each phase has specific functions related to cell growth and division.

2. **Analyzing the M Phase**:
- The M phase (mitotic phase) is when the cell divides. This phase includes karyokinesis (division of the nucleus) and cytokinesis (division of the cytoplasm). During this phase, DNA is already duplicated, so this cannot be the correct answer.

3. **Analyzing the S Phase**:
- The S phase (synthesis phase) is specifically when DNA replication occurs. The cell synthesizes a complete copy of the DNA in preparation for cell division. Since this phase involves DNA duplication, it is not the correct answer.

4. **Analyzing the G2 Phase**:
- The G2 phase is the second gap phase following the S phase. During this phase, the cell continues to grow and prepares for mitosis. There is also some synthesis of proteins and organelles, but DNA duplication has already occurred in the S phase. Therefore, this phase does not fit the criteria of being metabolically active without DNA duplication.

5. **Analyzing the G1 Phase**:
- The G1 phase (first gap phase) occurs before the S phase. During G1, the cell is metabolically active, engaging in various cellular processes such as protein synthesis, cell growth, and metabolism. Importantly, there is no DNA duplication during this phase. Thus, this is the correct answer.

### Conclusion:
The correct answer to the question is **G1 phase**, as it is the phase where the cell is metabolically active without any duplication of DNA.

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