The following is incorrect with regard to meiosis

Options

A. Nuclear envelope disappears twice
B. Nuclear envelope reappears twice
C. DNA content of daughter cells is reduced to `1//4^(th)` of Parental cell
D. DNA replicates twice

Answer

To determine which statement is incorrect with regard to meiosis, let's analyze each option provided in the question step by step.

### Step 1: Understand the process of meiosis
Meiosis is a type of cell division that reduces the chromosome number by half, resulting in four haploid daughter cells from one diploid parent cell. This process consists of two successive divisions: meiosis I and meiosis II.

### Step 2: Analyze the statements
1. **Nuclear envelope disappears twice**:
- In meiosis, the nuclear envelope breaks down during prophase I and again during prophase II. Therefore, this statement is **true**.

2. **Nuclear envelope reappears twice**:
- The nuclear envelope reforms after telophase I and again after telophase II. Hence, this statement is also **true**.

3. **DNA content of the daughter cell is reduced to one fourth of the parent cell**:
- During meiosis, the DNA content is indeed reduced from diploid (2n) to haploid (n) in the daughter cells. Since one diploid cell gives rise to four haploid cells, the DNA content is effectively reduced to one fourth. This statement is **true**.

4. **DNA replicates twice**:
- DNA replication occurs only once during the S phase of interphase before meiosis begins. It does not replicate again during the two meiotic divisions. Therefore, this statement is **false**.

### Conclusion
The incorrect statement regarding meiosis is that "DNA replicates twice."

### Final Answer
The following statement is incorrect with regard to meiosis: **DNA replicates twice.**

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