Oedema is caused due to  

Options

A. rise in globulin
B. fall in fibrinogen
C. fall in albumin
D. all the above

Answer

**Step-by-Step Solution:**

1. **Understanding Oedema**: Oedema is defined as fluid retention in the body. It occurs when excess fluid accumulates in the tissues, leading to swelling. This condition is often observed around areas such as the ankles.

2. **Mechanism of Oedema**: Oedema typically arises when there is a leak of fluid from small blood vessels, particularly capillaries, into surrounding tissues. This leakage can be caused by various factors, including changes in blood protein levels.

3. **Analyzing the Options**:
- **Option A: Rise in Globulin**: An increase in globulin levels usually indicates an infection or immune disorder. This does not directly cause oedema.
- **Option B: Fall in Fibrinogen**: A decrease in fibrinogen can lead to issues with blood clotting, but it is not a direct cause of fluid retention in tissues.
- **Option C: Fall in Albumin**: Albumin is a protein that helps maintain oncotic pressure in the blood vessels. A decrease in albumin levels can lead to fluid leaking from the blood vessels into the surrounding tissues, causing oedema.
- **Option D: All of the Above**: This option suggests that all the factors contribute to oedema, which is not accurate based on the analysis of the previous options.

4. **Conclusion**: The primary cause of oedema among the given options is a fall in albumin levels. Therefore, the correct answer is **Option C: Fall in Albumin**.

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