Huntington's disease is due to a dominant autosomal gene located on

Options

A. Chromosome 4
B. Chromosome 6
C. Chromosome 9
D. Chromosome 12

Answer

**Step-by-Step Solution:**

1. **Understanding Huntington's Disease**:
- Huntington's disease is a genetic disorder that leads to the progressive breakdown of nerve cells in the brain. It is characterized by movement disorders, cognitive decline, and psychiatric issues.

2. **Inheritance Pattern**:
- This disease is inherited in an autosomal dominant manner, meaning that only one copy of the defective gene from an affected parent can cause the disease in the offspring.

3. **Identifying the Chromosome**:
- The question asks for the specific chromosome on which the gene responsible for Huntington's disease is located.

4. **Reviewing the Options**:
- The options provided are chromosome 4, chromosome 6, chromosome 9, and chromosome 12.

5. **Researching Chromosome Functions**:
- Chromosome 4 is known to harbor the gene responsible for Huntington's disease.
- Chromosome 6 is associated with certain physical and intellectual disabilities.
- Chromosome 9 is linked to genital abnormalities and body deformities.
- Chromosome 12 is also associated with physical and mental disabilities.

6. **Selecting the Correct Answer**:
- Based on the information gathered, chromosome 4 is the correct answer as it contains the gene that causes Huntington's disease.

**Final Answer**: Huntington's disease is due to a dominant autosomal gene located on **chromosome 4**.

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