Lack of pigmentation in skin, hair and iris are thecharacteristics features of

Options

A. Alkaptonuria
B. Albinism
C. Tray-Sach's disease
D. Alzheimer's disease

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks us to identify a condition characterized by a lack of pigmentation in skin, hair, and iris.

2. **Analyzing the Options**: The options provided are:
- Alcaptonuria
- Albinism
- Tay-Sachs disease
- Alzheimer's disease

3. **Defining Albinism**: Albinism is an inherited disorder caused by the absence of the pigment melanin. This results in little or no pigmentation in the skin, hair, and eyes.

4. **Identifying Symptoms of Albinism**: Individuals with albinism typically have:
- Very light skin, hair, and eye color.
- Increased sensitivity to sunlight.
- A higher risk of skin cancer due to lack of melanin.

5. **Evaluating Other Options**:
- **Alcaptonuria**: A genetic metabolic disorder caused by the accumulation of homogentisic acid, not related to pigmentation.
- **Tay-Sachs Disease**: A neurological disorder that affects nerve cells in the brain and spinal cord, with no relation to pigmentation.
- **Alzheimer's Disease**: A progressive neurological disorder characterized by brain cell death, with no pigmentation symptoms.

6. **Conclusion**: Based on the analysis, the correct answer is **Albinism**.

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