The Cri-du-Chat Syndrome is Caused by Changed in Chromosome Structure involving

Options

A. Deletion
B. Duplication
C. Inversion
D. Translocation

Answer

**Step-by-Step Solution:**

1. **Understanding Cri-du-Chat Syndrome**:
- Cri-du-Chat Syndrome, also known as "cat's cry syndrome," is a genetic disorder that results from a chromosomal abnormality.

2. **Identifying the Chromosome Involved**:
- The syndrome is specifically associated with a deletion on chromosome 5.

3. **Chromosome Structure Changes**:
- Chromosomal abnormalities can occur in several forms, including deletion, duplication, inversion, and translocation.

4. **Determining the Type of Change**:
- In the case of Cri-du-Chat Syndrome, the critical change is the deletion of a portion of chromosome 5. This means that part of the chromosome is missing.

5. **Conclusion**:
- Therefore, the correct answer to the question is that Cri-du-Chat Syndrome is caused by changes in chromosome structure involving **deletion**.

**Final Answer**: The Cri-du-Chat Syndrome is caused by changes in chromosome structure involving deletion.

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