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Which one pair of the parents out of the...

Which one pair of the parents out of the following is most likely to get a child who would suffer from hemolytic disease of the new born.

A

`Rh^(+)` morther & `Rh^(-)` father

B

`Rh^(-)` mother & `Rh^(-)` father

C

`Rh^(+)` mother & `Rh^(+)` father

D

`Rh^(-)` mother & `Rh^(+)` father

Text Solution

AI Generated Solution

The correct Answer is:
To determine which pair of parents is most likely to have a child suffering from hemolytic disease of the newborn (HDN), we need to understand the genetic basis of this condition. ### Step-by-Step Solution: 1. **Understand Hemolytic Disease of the Newborn (HDN)**: - HDN, also known as erythroblastosis fetalis, occurs when there is an incompatibility between the blood types of the mother and the fetus, specifically concerning the Rh factor. 2. **Identify the Key Factors**: - The condition typically arises when the mother is Rh negative (Rh-) and the fetus is Rh positive (Rh+). This is because the mother can produce antibodies against the Rh factor if exposed to Rh+ blood. 3. **Analyze the Parent Pairs**: - We have four pairs of parents to consider: 1. Rh+ mother and Rh- father 2. Rh- mother and Rh- father 3. Rh+ mother and Rh+ father 4. Rh- mother and Rh+ father 4. **Evaluate Each Pair**: - **Pair 1**: Rh+ mother and Rh- father - The child can only be Rh+ or Rh- (not likely to cause HDN). - **Pair 2**: Rh- mother and Rh- father - The child will definitely be Rh- (no risk of HDN). - **Pair 3**: Rh+ mother and Rh+ father - The child will be Rh+ (no risk of HDN). - **Pair 4**: Rh- mother and Rh+ father - The child can be Rh+ (this is the scenario that can lead to HDN). 5. **Conclusion**: - The pair most likely to have a child suffering from hemolytic disease of the newborn is **Rh- mother and Rh+ father** (Option 4). ### Final Answer: The correct answer is **Option 4: Rh- mother and Rh+ father**. ---
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