Haemophila -A is due to the deficiency of

Options

A. Anti haemophilic globulin
B. plasms thromboplastin component
C. Plasma thromboplastin antecedant
D. Tissue thromboplastin

Answer

**Step-by-Step Solution:**

1. **Understanding Hemophilia A**: Hemophilia A is a genetic disorder characterized by the inability of blood to clot properly, leading to excessive bleeding even from minor injuries.

2. **Identifying the Cause**: The primary cause of Hemophilia A is the deficiency of a specific clotting factor. In this case, it is essential to identify which clotting factor is deficient.

3. **Clotting Factor Involved**: Hemophilia A is specifically associated with the deficiency of clotting factor VIII (Factor 8). This factor is crucial for the blood coagulation process.

4. **Alternative Names**: Clotting factor VIII is also known as anti-hemophilic factor. This alternative name is important for understanding the options provided in the question.

5. **Genetic Basis**: The gene responsible for encoding clotting factor VIII is the F8 gene, which is located on the X chromosome. This makes Hemophilia A an X-linked recessive disorder.

6. **Evaluating Options**: The options given in the question are:
- A) Anti-hemophilia globulin
- B) Plasma thromboplastin component
- C) Plasma thromboplastin antecedent
- D) Tissue thromboplastin

Among these, the correct answer is option A, as anti-hemophilia globulin is another name for clotting factor VIII.

7. **Conclusion**: Therefore, Hemophilia A is due to the deficiency of anti-hemophilia globulin (clotting factor VIII).

**Final Answer**: Hemophilia A is due to the deficiency of anti-hemophilia globulin (clotting factor VIII).

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