Mark the wrong statement about denaturation of proteins

Options

A. The primary structure of the protein does not change
B. Globular proteins are converted into fibrous proteins
C. Fibrous proteins are converted into globular
D. The biological activity of the protein is cancelled

Answer

To determine the wrong statement about the denaturation of proteins, let's analyze each of the provided options step by step.

### Step 1: Understand Denaturation of Proteins
Denaturation refers to the process where proteins lose their native structure due to external stress or compounds, such as heat, acid, or chemicals. This process affects the protein's secondary, tertiary, and quaternary structures, but not the primary structure.

### Step 2: Analyze Each Statement
1. **Primary structure of protein does not change.**
- This statement is **true**. The primary structure, which is the sequence of amino acids, remains intact during denaturation.

2. **Globular proteins are converted into fibrous proteins.**
- This statement is **true**. During denaturation, globular proteins can unfold and aggregate, leading to a fibrous structure.

3. **Fibrous proteins are converted into globular.**
- This statement is **false**. Fibrous proteins do not convert into globular proteins during denaturation; instead, globular proteins can become fibrous.

4. **Biological activity of protein is cancelled.**
- This statement is **true**. Denaturation typically results in the loss of biological activity of the protein.

### Step 3: Identify the Wrong Statement
From the analysis, the wrong statement about denaturation of proteins is:
- **Fibrous proteins are converted into globular.**

### Final Answer
The wrong statement about denaturation of proteins is: **Fibrous proteins are converted into globular.**

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