In nucleic acids, the nucleotides are linked to one another through

Options

A. Hydrogen bond
B. Peptide bond
C. Glycosidic linkage
D. Phosphate groups

Answer

To solve the question regarding how nucleotides are linked to one another in nucleic acids, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Structure of Nucleotides**:
- Nucleotides are the building blocks of nucleic acids (DNA and RNA) and consist of three components: a phosphate group, a sugar molecule (ribose in RNA and deoxyribose in DNA), and a nitrogenous base.

2. **Identify the Linkage in Nucleic Acids**:
- Nucleotides are connected to each other to form a nucleic acid strand. The connection occurs between the phosphate group of one nucleotide and the sugar of the next nucleotide.

3. **Determine the Type of Bond**:
- The bond that forms between the phosphate group of one nucleotide and the sugar of another nucleotide is known as a **phosphodiester bond**. This bond is crucial for the formation of the sugar-phosphate backbone of nucleic acids.

4. **Evaluate the Given Options**:
- Option A: Hydrogen bond - This type of bond occurs between complementary nitrogenous bases (e.g., A-T and G-C pairs) but does not link nucleotides in a strand.
- Option B: Peptide bond - This bond links amino acids in proteins, not nucleotides in nucleic acids.
- Option C: Glycosidic linkage - This bond connects the sugar to the nitrogenous base within a nucleotide, not between nucleotides.
- Option D: Phosphate groups - While they are involved in the linkage, they do not represent the type of bond formed between nucleotides.

5. **Conclusion**:
- The correct answer to the question is that nucleotides are linked to one another through **phosphodiester bonds**.

### Final Answer:
Nucleotides in nucleic acids are linked to one another through **phosphodiester bonds**.