During the replication of DNA, one of the strands is synthesized in pieces and are joined latter in the presence of enzyme called

Options

A. RNA ligase
B. DNA ligase
C. r-RNA
D. m-RNA

Answer

**Step-by-Step Solution:**

1. **Understanding DNA Replication**: During DNA replication, the double-stranded DNA unwinds and separates into two single strands. Each strand serves as a template for the synthesis of a new complementary strand.

2. **Identifying the Strands**: One of the strands, known as the leading strand, is synthesized continuously in the direction of the replication fork. The other strand, called the lagging strand, is synthesized in short segments known as Okazaki fragments.

3. **Joining the Fragments**: After the Okazaki fragments are synthesized, they need to be joined together to form a continuous strand. This is where an enzyme comes into play.

4. **Identifying the Enzyme**: The enzyme responsible for joining the Okazaki fragments on the lagging strand is called DNA ligase. DNA ligase catalyzes the formation of phosphodiester bonds between the fragments, effectively sealing the gaps.

5. **Conclusion**: Therefore, the enzyme that joins the pieces of the lagging strand during DNA replication is DNA ligase.

**Final Answer**: The enzyme is DNA ligase.

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