Which of the following statements is/are correct?

Options

A. Hepatitis B virus (HBV) can be transmitted through contamination
B. Hepatitis B virus vaccine is the second generation vaccine produced from transgenic yeast by recombinant DNA technology
C. Hepatitis B virus vaccine is made of attenuated whole agent vaccines.
D. All of these

Answer

To determine which statements about the hepatitis B virus are correct, we will analyze each statement one by one.

### Step-by-Step Solution:

1. **Analyze the First Statement:**
- The statement claims that the hepatitis B virus can be transmitted through contamination.
- **Evaluation:** This statement is correct. Hepatitis B virus (HBV) can be transmitted through contaminated needles, syringes, and other means of exposure to infected bodily fluids.

2. **Analyze the Second Statement:**
- The statement claims that the hepatitis B virus vaccine is a second-generation vaccine produced from transgenic yeast by recombinant DNA technology.
- **Evaluation:** This statement is also correct. The hepatitis B vaccine is indeed produced using recombinant DNA technology, and it involves the use of yeast to produce the surface antigens of the virus.

3. **Analyze the Third Statement:**
- The statement claims that the hepatitis B virus vaccine is made of attenuated collagen vaccine.
- **Evaluation:** This statement is incorrect. The hepatitis B vaccine is not made from an attenuated virus; rather, it is a subunit vaccine that contains purified proteins from the virus (specifically, the surface antigens).

4. **Conclusion:**
- Based on the evaluations, the first and second statements are correct, while the third statement is incorrect. Therefore, the correct answer is that options A and B are correct.

### Final Answer:
The correct statements are:
- The hepatitis B virus can be transmitted through contamination (Correct).
- The hepatitis B virus vaccine is a second-generation vaccine produced from transgenic yeast by recombinant DNA technology (Correct).
- The statement about the vaccine being made of attenuated collagen is incorrect.

Thus, the answer is that the first two statements are correct.

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