rDNA technology is used in developing vaccines against

Options

A. Tetanus
B. Polio
C. Small pox
D. Hepatitis B

Answer

To answer the question "rDNA technology is used in developing vaccines against," we will analyze the options provided and determine which vaccine is developed using recombinant DNA technology.

### Step-by-Step Solution:

1. **Understand rDNA Technology**: Recombinant DNA (rDNA) technology involves inserting DNA of interest into a host cell. This process allows for the production of proteins or antigens that can be used in vaccines.

2. **Evaluate the Options**:
- **Option 1: Tetanus**: The tetanus vaccine is typically made from inactivated tetanospasmin toxin, not through rDNA technology.
- **Option 2: Polio**: The polio vaccine is made using inactivated or live attenuated poliovirus, not through rDNA technology.
- **Option 3: Smallpox**: The smallpox vaccine is derived from the vaccinia virus and does not utilize rDNA technology.
- **Option 4: Hepatitis B**: The Hepatitis B vaccine is produced using recombinant DNA technology. It involves inserting the gene for the Hepatitis B surface antigen into yeast cells, which then produce the antigen that is used in the vaccine.

3. **Identify the Correct Answer**: Based on the evaluation, the only vaccine developed using rDNA technology is the Hepatitis B vaccine.

4. **Conclusion**: Therefore, the correct answer to the question is **Option 4: Hepatitis B**.