Vaccines produced through genetic engineering are safe as

Options

A. they are least active form of virus
B. they are attenuated form of pathogen
C. they contain antigen only from coat of pathogen
D. all of these

Answer

**Step-by-Step Solution:**

1. **Understanding Vaccines**: Vaccines are biological preparations that provide acquired immunity to a particular infectious disease. They typically contain an agent that resembles a disease-causing microorganism.

2. **Genetic Engineering in Vaccines**: Vaccines produced through genetic engineering involve the use of specific genes from pathogens (like viruses) to create antigens. These antigens are the parts of the pathogen that trigger an immune response.

3. **Safety of Genetically Engineered Vaccines**: The safety of these vaccines comes from the fact that they often contain only specific components of the pathogen (like the protein coat) rather than the whole pathogen itself. This minimizes the risk of causing disease.

4. **Comparison with Conventional Vaccines**: Conventional vaccines may use live attenuated (weakened) or killed versions of the pathogen. While effective, these can sometimes pose risks, especially in individuals with weakened immune systems.

5. **Conclusion**: Therefore, genetically engineered vaccines are considered safer because they primarily contain antigens derived from the pathogen's coat, which do not pose a risk of causing the disease.

6. **Correct Answer**: The correct answer to the question is option 3: "they contain antigen only from the coat of a pathogen."

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