In the metropolitan cities of India, many children are suffering from allergy or asthma. What are the main causes of this problem?
I. Due to sensitivity to the environment.
II. Because of the protected environment provided early in life.
III. Modern-day life style.

Options

A. I and II
B. I and III
C. II and III
D. I, II and III

Answer

### Step-by-Step Solution:

1. **Understanding Allergy and Asthma**:
- Allergy is an overreaction of the immune system to harmless substances (like pollen), where the body produces antibodies (IgE) against them.
- Asthma is a respiratory condition characterized by the contraction and swelling of airways, leading to symptoms like coughing, wheezing, and breathlessness.

2. **Identifying the Context**:
- The question focuses on children in metropolitan cities of India suffering from allergies and asthma.

3. **Analyzing the Causes**:
- **Cause I: Sensitivity to the Environment**:
- Children in urban areas are often exposed to various environmental pollutants and allergens, which can trigger allergic reactions and asthma.
- **Cause II: Protected Environment**:
- Many children grow up in controlled environments (homes with air purifiers, filters) that limit their exposure to pathogens. This lack of exposure can prevent the development of acquired immunity, making their immune systems overly sensitive.
- **Cause III: Modern-Day Lifestyle**:
- The lifestyle of children today often involves less outdoor play and interaction with the environment, which can lead to a lack of exposure to various antigens that help build a robust immune system.

4. **Conclusion**:
- The main causes of allergies and asthma in children in metropolitan cities are:
- **II**: Because of the protected environment provided early in life.
- **III**: Modern-day lifestyle.
- Therefore, the correct answer is options II and III.

### Final Answer:
The main causes of allergy and asthma in children in metropolitan cities are:
- II. Because of the protected environment provided early in life.
- III. Modern-day lifestyle.